Publications
The TAHS studies asthma, Chronic Obstructive Pulmonary Disease (COPD) and other allergies. Our research looks into the natural history, lifestyle, environmental and genetic risk factors of these diseases and conditions. Our goal is to identify the causes and how best to prevent these interrelated diseases, which are major public health issues.
You can read about our research themes and published papers below. If you would like to read one of our published papers but do not have access, please fill out an inquiry form and include the paper title in the subject line; we will provide you with a pdf version. Alternatively, you can call us on 1800 110 711
TAHS research themes
Allergic sensitization occurs when the body becomes sensitive (allergic) to environmental allergens such as grass, pollens, air pollution, mold, and house dust mites. When a person becomes sensitized to a particular allergen, the body learns to develop an inflammatory response every time the allergen is re-exposed. Different allergens also have different relationships with allergic diseases. Sensitization to house dust mites, for example, is more commonly linked to asthma, whereas sensitization to pollens is more commonly linked to allergic rhinitis (hay fever). When the body triggers an immune response, it produces substances in your bloodstream (known as cytokines) that can be detected and measured. High levels of Nitric Oxide (a gas) are also released when the airways become inflamed and can be detected in your breath. The TAHS used skin prick tests to look at allergic reactions to a variety of allergens and discovered several cytokines linked to particular allergens. According to the TAHS findings, people who have a mutation of the gene called CD14 may be at a higher risk of developing allergic sensitization. But interestingly, if a person is exposed to a sibling early in life, this risk can be minimized.
4 Publications for allergic sensitisation
- Mold-sensitized adults have lower Th2 cytokines and a higher prevalence of asthma than those sensitized to other aeroallergens – 2016
- Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age – 2017
- NO x in exhaled breath condensate is related to allergic sensitization in young and middle-aged adults – 2018
- Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization – 2019
Australians breathe some of the cleanest air in the world. But even in a low-polluted setting, it is enough to cause respiratory problems. Air pollution consists of small particles such as smoke, dirt, pollen, mould, or other substances. The smaller the particle size, the easier it is to penetrate deeper into the lungs, where the chemicals on these particles can trigger airway irritation which can affect breathing. The TAHS studies found a link between higher concentrations of air pollution exposure and a higher risk for asthma, poor lung function, higher risk of developing allergies and eczema. The studies also found people who live closer to major roads are at greater risk for these conditions.
9 publications for air pollution
- Ambient wood smoke, traffic pollution and adult asthma prevalence and severity – 2013
- Domestic airborne pollutants and asthma and respiratory symptoms in middle age – 2014
- Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age – 2017
- The Dose-Response Association between Nitrogen Dioxide Exposure and Serum Interleukin-6 Concentrations – 2017
- Traffic-related air pollution exposure over a 5-year period is associated with increased risk of asthma and poor lung function in middle age – 2017
- Traffic-related air pollution and development and persistence of asthma and low lung function – 2018
- Residential Exposure to Outdoor Air Pollution and Post-bronchodilator Lung Function Deficits in Mid-Adult Life – 2019
- Exposure to household air pollution over 10 years is related to asthma and lung function decline – 2021
- Association between ambient air pollution and development and persistence of atopic and non-atopic eczema in a cohort of adults – 2021
While Australia has one of the highest asthma prevalence rates worldwide, the causes of asthma are still unclear. Over the years, the TAHS has expanded our understanding of the risk factors for developing asthma. According to the TAHS findings, asthma can be caused by several factors, including a genetic tendency (those who carry particular genes are more likely to develop asthma), smoking, or by inhaling substances and particles that irritate the airways and cause allergic reactions. These substances may be air pollution, aeroallergens (such as pollens and spores), or other toxic chemicals in the household or at the workplace. Childhood risk factors such as hay fever and eczema can also increase the risk of developing asthma and having persistent asthma symptoms that last to adulthood. The TAHS studies also showed that having a poor asthma management plan is linked to asthma persistence and more severe symptoms.
43 publications for asthma
- The use of discriminant analysis in the detection of geographic types of asthma– 1980
- Respiratory symptoms in Tasmanian adolescents: a follow up of the 1961 birth cohort – 1984
- The associations between childhood asthma and atopy, and parental asthma, hay fever and smoking – 1993
- Factors in childhood as predictors of asthma in adult life – 1994
- Increase in the self-reported prevalence of asthma and hay fever in adults over the last generation: a matched parent-offspring study – 1995
- Validation of Questionnaire and Bronchial Hyperresponsiveness against Respiratory Physician Assessment in the Diagnosis of Asthma – 1996
- Regressive logistic modeling of familial aggregation for asthma in 7,394 population-based nuclear families – 1997
- Who remembers whether they had asthma as children? – 2006
- Parity and decreased use of oral contraceptives as predictors of asthma in young women – 2006
- Childhood adiposity predicts adult-onset current asthma in females: a 25-yr prospective study – 2007
- Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study – 2007
- Childhood eczema and asthma incidence and persistence: a cohort study from childhood to middle age– 2008
- Adherence to asthma management guidelines by middle-aged adults with current asthma – 2009
- Factors influencing asthma remission: a longitudinal study from childhood to middle age -2011
- Childhood eczema and rhinitis predict atopic but not nonatopic adult asthma: a prospective cohort study over 4 decades – 2011
- Identification of IL6R and chromosome 11q13.5 as risk loci for asthma – 2011
- Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA – 2012
- Childhood infections and the risk of asthma over time: a longitudinal study over 37 years – 2012
- Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data – 2012
- Genome-wide association study to identify genetic determinants of severe asthma – 2012
- The Interplay between the Effects of Lifetime Asthma, Smoking, and Atopy on Fixed Airflow Obstruction in Middle Age – 2013
- Ambient wood smoke, traffic pollution and adult asthma prevalence and severity – 2013
- Occupational exposures and the development of new-onset asthma: a population-based cohort study from the ages of 13 to 44 years– 2013
- Adult Serum Cytokine Concentrations and the Persistence of Asthma – 2013
- Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype – 2014
- Domestic airborne pollutants and asthma and respiratory symptoms in middle age – 2014
- The independent and combined effects of lifetime smoke exposures and asthma as they relate to COPD – 2014
- Hormonal contraception increases risk of asthma among obese but decreases it among nonobese subjects: a prospective, population-based cohort study – 2015
- Preterm birth and low birth weight continue to increase the risk of asthma from age 7 to 43 – 2016
- Mold-sensitized adults have lower Th2 cytokines and a higher prevalence of asthma than those sensitized to other aeroallergens – 2016
- Clinical and functional differences between early-onset and late-onset adult asthma: a population-based Tasmanian Longitudinal Health Study – 2016
- Current asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study – 2016
- Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age – 2017
- The interaction between farming/rural environment and TLR2, TLR4, TLR6 and CD14 genetic polymorphisms in relation to early- and late-onset asthma – 2017
- Long-term traffic-related air pollution exposure is associated with increased risk of asthma and poor lung function in middle age – 2017
- Childhood Lung Function Predicts Adult Chronic Obstructive Pulmonary Disease and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome – 2017
- Traffic-related air pollution exposure over a 5-year period is associated with increased risk of asthma and poor lung function in middle age – 2017
- Traffic-related air pollution and development and persistence of asthma and low lung function – 2018
- Trajectories of asthma and allergies from 7 years to 53 years and associations with lung function and extrapulmonary comorbidity profiles: a prospective cohort study – 2020
- Non-pharmacological management of adult asthma in Australia: cross-sectional analysis of a population-based cohort study – 2020
- Exposure to household air pollution over 10 years is related to asthma and lung function decline – 2021
- Bronchodilator reversibility as a diagnostic test for adult asthma: findings from the population-based Tasmanian Longitudinal Health Study – 2021
- Longitudinal Asthma Phenotypes from Childhood to Middle-Age: A Population-based Cohort Study – 2023
Few cohort studies in the world are able to study the natural course of asthma and other chronic obstructive pulmonary disorders (COPD) from childhood through adulthood. The TAHS cohort is unique in that we have been monitoring our participants since childhood. We have been gathering data on respiratory symptoms and performing lung function tests all along the way. This allowed us to track changes in childhood lung function and respiratory conditions. We then came up with models to predict those that are more likely to be on the path to poor lung health in adulthood. Based on the TAHS findings, adults that have COPD-like breathing patterns and poor lung function features can be traced back to childhood causes such as asthma, bronchitis, pneumonia, allergic rhinitis, eczema, parental asthma, and maternal smoking.
20 publications for childhood risk factors
- The associations between childhood asthma and atopy, and parental asthma, hay fever and smoking– 1993
- Factors in childhood as predictors of asthma in adult life– 1994
- Childhood adiposity predicts adult-onset current asthma in females: a 25-yr prospective study– 2007
- Is childhood immunisation associated with atopic disease from age 7 to 32 years? – 2007
- Breast-feeding and atopic disease: A cohort study from childhood to middle age – 2007
- Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study– 2007
- Childhood eczema and asthma incidence and persistence: a cohort study from childhood to middle age– 2008
- Childhood immunization and atopic disease into middle-age–a prospective cohort study – 2010
- Poor lung function and tonsillectomy in childhood are associated with mortality from age 18 to 44 – 2010
- Factors influencing asthma remission: a longitudinal study from childhood to middle age-2011
- Childhood eczema and rhinitis predict atopic but not nonatopic adult asthma: a prospective cohort study over 4 decades– 2011
- Childhood infections and the risk of asthma over time: a longitudinal study over 37 years– 2012
- Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data– 2012
- Association between latitude and allergic diseases: a longitudinal study from childhood to middle-age – 2013
- Childhood body mass index and adult mammographic density measures that predict breast cancer risk – 2016
- Childhood Lung Function Predicts Adult Chronic Obstructive Pulmonary Disease and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome– 2017
- Childhood measles contributes to post-bronchodilator airflow obstruction in middle-aged adults: A cohort study – 2018
- Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life – 2018
- Childhood Respiratory Risk Factor Profiles and Middle-Age Lung Function: A Prospective Cohort Study from the First to Sixth Decade – 2018
- Childhood pneumonia, pleurisy and lung function: a cohort study from the first to sixth decade of life – 2020
As you may recall, at each of the clinical studies over the years since 1968, you may have had a spirometry test. This simple breathing test looks at the overall health of the lungs by measuring how much air can be inhaled and exhaled, and how quickly the air is exhaled. Other tests the TAHS performed include gas diffusing capacity (how well the lungs can deliver oxygen to your blood) and pulse oximetry (measures the amount of oxygen in your blood). Chronic Obstructive Pulmonary Diseases (COPD), asthma, and other diseases that impair breathing patterns are detected using these measurements.
26 Publications for detecting chronic obstructive lung diseases
- The interrelationships of upper and lower respiratory tract symptoms and signs in seven-year-old children – 1972
- Validation of Questionnaire and Bronchial Hyperresponsiveness against Respiratory Physician Assessment in the Diagnosis of Asthma – 1996
- The Interplay between the Effects of Lifetime Asthma, Smoking, and Atopy on Fixed Airflow Obstruction in Middle Age – 2013
- Mother’s smoking and complex lung function of offspring in middle age: A cohort study from childhood – 2016
- Current asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study – 2016
- Clinical and functional differences between early-onset and late-onset adult asthma: a population-based Tasmanian Longitudinal Health Study – 2016
- Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age – 2017
- Long-term traffic-related air pollution exposure is associated with increased risk of asthma and poor lung function in middle age – 2017
- Bronchial hyperresponsiveness and obesity in middle age: insights from an Australian cohort – 2017
- Occupational exposures to solvents and metals are associated with fixed airflow obstruction – 2017
- Occupational exposure to pesticides are associated with fixed airflow obstruction in middle-age – 2017
- Childhood Lung Function Predicts Adult Chronic Obstructive Pulmonary Disease and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome – 2017
- Traffic-related air pollution exposure over a 5-year period is associated with increased risk of asthma and poor lung function in middle age – 2017
- Traffic-related air pollution and development and persistence of asthma and low lung function – 2018
- Childhood measles contributes to post-bronchodilator airflow obstruction in middle-aged adults: A cohort study – 2018
- Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life – 2018
- Residential Exposure to Outdoor Air Pollution and Post-bronchodilator Lung Function Deficits in Mid-Adult Life -2019
- Occupational exposure to solvents and lung function decline: A population based study – 2019
- Nocturnal symptoms perceived as asthma are associated with obstructive sleep apnoea risk, but not bronchial hyper-reactivity – 2019
- Trajectories of asthma and allergies from 7 years to 53 years and associations with lung function and extrapulmonary comorbidity profiles: a prospective cohort study – 2020
- Lifetime Risk Factors for Pre- and Post-Bronchodilator Lung Function Decline. A Population-based Study – 2020
- Childhood pneumonia, pleurisy and lung function: a cohort study from the first to sixth decade of life – 2020
- Early Age at Natural Menopause Is Related to Lower Post-Bronchodilator Lung Function. A Longitudinal Population-based Study – 2020
- Early menarche is associated with lower adult lung function: A longitudinal cohort study from the first to sixth decade of life – 2020
- Exposure to household air pollution over 10 years is related to asthma and lung function decline – 2021
- Bronchodilator reversibility as a diagnostic test for adult asthma: findings from the population-based Tasmanian Longitudinal Health Study – 2021
Eczema, also known as atopic dermatitis, is a skin condition that is more common in children than in adults. A person with eczema experiences itchiness and may have inflamed patches of red rash on the skin. Eczema is thought to be caused by an overactive immune system that reacts aggressively to irritants in the environment (such as air pollution, cleaning chemicals and rough, scratchy clothing materials). This overactive immune system can also make the person more likely to develop other types of allergies. But it is also possible to have non-atopic eczema, in which the immune system is non-overactive. The TAHS studies found those with childhood eczema are also more likely to have childhood asthma, more likely to develop asthma later in life (also known as new-onset asthma), and have asthma persisting into middle age.
10 publications for eczema
- The associations between childhood asthma and atopy, and parental asthma, hay fever and smoking– 1993
- Factors in childhood as predictors of asthma in adult life– 1994
- Is childhood immunisation associated with atopic disease from age 7 to 32 years?– 2007
- Childhood eczema and asthma incidence and persistence: a cohort study from childhood to middle age– 2008
- Childhood immunization and atopic disease into middle-age–a prospective cohort study– 2010
- Childhood eczema and rhinitis predict atopic but not nonatopic adult asthma: a prospective cohort study over 4 decades– 2011
- Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data– 2012
- Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life– 2018
- Trajectories of asthma and allergies from 7 years to 53 years and associations with lung function and extrapulmonary comorbidity profiles: a prospective cohort study– 2020
- Association between ambient air pollution and development and persistence of atopic and non-atopic eczema in a cohort of adults– 2021
The TAHS conducted several gene studies over the years to examine how a person’s genetic makeup (their genome) can influence their risk of developing respiratory diseases. Genome-Wide Association Study (GWAS) is a method of scanning a person’s genome to look for differences in particular genes and see whether these variations are related to having the disease. The studies identified 11 different variations of a gene that were associated with having asthma and hay fever. One gene called Filaggrin can increase the risk for eczema. Surprisingly, the TAHS studies discovered that living on a farm or in a rural area can alter a person’s risk of developing eczema or allergies, even though they have the genes that put them at risk.
7 publications for genes and their interplay with the environment
- Identification of IL6R and chromosome 11q13.5 as risk loci for asthma– 2011
- Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA– 2012
- Genome-wide association study to identify genetic determinants of severe asthma– 2012
- Association between latitude and allergic diseases: a longitudinal study from childhood to middle-age – 2013
- Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype– 2014
- The interaction between farming/rural environment and TLR2, TLR4, TLR6 and CD14 genetic polymorphisms in relation to early- and late-onset asthma– 2017
- Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization – 2019
Hay fever, also known as allergic rhinitis, is the most common allergic disorder in Australia. Hay fever is triggered when the immune system overreacts to allergens in the air (such as house dust, animal fur, pollens, fungal spores, and other air pollutants). The TAHS studies found several genes that are linked to the likelihood of developing hay fever. There are also several other factors that increase the risk of developing hay fever early on in life. Amongst other childhood factors, having eczema during infancy and having a tonsillectomy (tonsils removal) seem to be related to a higher risk for hay fever. Interestingly, the more viral infections a person had during childhood, the less likely they were to develop hay fever in childhood. It is also important to recognize other unpleasant effects of hayfever, such as an increased risk of developing asthma early on in life and experiencing asthma symptoms that last from childhood to adulthood.
6 publications for hay fever
- Increase in the self-reported prevalence of asthma and hay fever in adults over the last generation: a matched parent-offspring study– 1995
- Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study– 2007
- Relevance of the hygiene hypothesis to early vs. late onset allergic rhinitis – 2009
- Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data– 2012
- Association between latitude and allergic diseases: a longitudinal study from childhood to middle-age – 2013
- Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype– 2014
Being overweight or obese refers to having excess fat around the body, which is a risk factor for many diseases and chronic conditions, including asthma and sleep apnoea. Excess fat around the neck or chest may put pressure on the airways and lungs, making deep breathing difficult. Being overweight also prompts the body to produce hormones and chemicals that affects the breathing patterns by thickening the airways. The TAHS studies found that obese people are more likely to have more narrowed airways during normal breathing and are more likely to have lung function decline in adulthood. Another study also found that among non-asthmatic young females (7 years old), those with a higher body mass index are more likely to develop asthma in adulthood.
5 publications for obesity
- Childhood adiposity predicts adult-onset current asthma in females: a 25-yr prospective study– 2007
- Hormonal contraception increases risk of asthma among obese but decreases it among nonobese subjects: a prospective, population-based cohort study– 2015
- Bronchial hyperresponsiveness and obesity in middle age: insights from an Australian cohort – 2017
- Detecting sleep apnoea syndrome in primary care with screening questionnaires and the Epworth sleepiness scale – 2019
- Lifetime Risk Factors for Pre- and Post-Bronchodilator Lung Function Decline. A Population-based Study – 2020
A person’s occupation and work environment can expose them to harmful substances that can damage their lungs. The TAHS studies found that exposure to dangerous substances such as pesticides, herbicides, gases/fumes, and mineral dust was related to fixed airflow obstruction (reduced ability to fully exhale air), chronic bronchitis (inflamed airways), and decline in lung function. These are linked to Chronic Obstructive Pulmonary Diseases (COPD). Exposure to metals and chemicals that contain chlorine are also important risk factors for fixed airflow obstruction. Women were at a higher risk than men. The TAHS also analyzed the risk for asthma in a group of people that were asthma-free at age 13. The studies found a strong association between the long-term (after 16 years) use of latex and new-onset asthma (asthma that develops later on in life).
4 publications for occupational exposures
- Occupational exposures and the development of new-onset asthma: a population-based cohort study from the ages of 13 to 44 years– 2013
- Occupational exposures to solvents and metals are associated with fixed airflow obstruction – 2017
- Occupational exposure to pesticides are associated with fixed airflow obstruction in middle-age – 2017
- Occupational exposure to solvents and lung function decline: A population based study – 2019
Many Australians are suffering from sleep apnoea, which prevents them from sleeping restfully. Sleep apnea is more than just loud snoring and feeling tired after a full night’s sleep. There is evidence that untreated sleep apnea can affect your ability to focus on tasks and jobs that need good concentration to do safely. It could also increase your blood pressure and put you at greater risk of heart and other health issues. Because of this, health care workers have trialed better ways to detect sleep apnoea in the general population. The TAHS studies aim to manage this sleep condition at an earlier time than people might normally see their doctor. Our findings helped policymakers to decide on the best way for general practitioners to refer their patients for an overnight sleep study. This will help sleep specialists and general practitioners in monitoring and treating patients in order to improve the overall sleep quality of Australian adults.
3 publications for sleep apnoea
- Detecting sleep apnoea syndrome in primary care with screening questionnaires and the Epworth sleepiness scale– 2019
- Nocturnal symptoms perceived as asthma are associated with obstructive sleep apnoea risk, but not bronchial hyper-reactivity– 2019
- Comparison of apnoea-hypopnoea index and oxygen desaturation index when identifying obstructive sleep apnoea using type-4 sleep studies – 2019
It isn’t new information that smoking is bad for your lungs because it damages the airways and small air sacs (known as alveoli). The TAHS studies confirmed that active smoking substantially contributed to Chronic Obstructive Pulmonary Diseases (COPD) in middle-age. They also showed strong links between smoking and having asthma, chronic bronchitis (inflamed airways), and increased breathing obstruction. Cigarette smoke (or secondhand smoke exposure) is also associated with a higher number of doctor-diagnosed asthma, higher risk for respiratory symptoms (wheezing, chest tightness). The TAHS findings also showed that mothers who were heavy smokers increased their children’s chances of developing COPD later in life.
6 publications for smoking
- Factors influencing asthma remission: a longitudinal study from childhood to middle age-2011
- The Interplay between the Effects of Lifetime Asthma, Smoking, and Atopy on Fixed Airflow Obstruction in Middle Age– 2013
- Domestic airborne pollutants and asthma and respiratory symptoms in middle age– 2014
- The independent and combined effects of lifetime smoke exposures and asthma as they relate to COPD– 2014
- Current asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study– 2016
- Mother’s smoking and complex lung function of offspring in middle age: A cohort study from childhood – 2016
It is not well recognized that changes in a woman’s natural menstrual phases may affect her lung health. The TAHS researchers looked into whether women with early menarche (when menstruation begins) and early menopause (when menstruation ends) had different lung functions than women with typical menarche and menopause phases. According to the findings, women who had early menarche (before 12 years) and those with earlier menopause (before 45 years) have reduced lung function. These women have slightly smaller lungs probably due to this earlier maturation.
3 publications for women’s health
- Childhood body mass index and adult mammographic density measures that predict breast cancer risk – 2016
- Early Age at Natural Menopause Is Related to Lower Post-Bronchodilator Lung Function. A Longitudinal Population-based Study – 2020
- Early menarche is associated with lower adult lung function: A longitudinal cohort study from the first to sixth decade of life – 2020
All publications
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Title Journal Year Authors
Respiratory disorders in seven-year-old children in Tasmania. Aims, methods and administration of the survey Medical Journal of Australia 1969 Heather B. Gibson,Harold Silverstone, Bryan Gandevia, Graham J. L. Hall
The interrelationships of upper and lower respiratory tract symptoms and signs in seven-year-old children International Journal of Epidemiology 1972 Graham J. L. Hall, Bryan Gandevia, Harold Silverstone, Joy H. A. Searle, Heather B. Gibson
What happens to wheezy children and why? Transactions of the Menzies Foundation 1980 Heather B Gibson , Graham G Giles
The use of discriminant analysis in the detection of geographic types of asthma Social Science & Medicine 1980 Graham G Giles
Respiratory symptoms in Tasmanian adolescents: a follow up of the 1961 birth cohort Australian and New Zealand Journal of Medicine 1984 Graham G. Giles, Norelle Lickiss, Heather B. Gibson, K Shaw
The associations between childhood asthma and atopy, and parental asthma, hay fever and smoking Paediatric and Perinatal Epidemiology 1993 Mark A Jenkins, John L Hopper, Louisa B Flander, John B Carlin, Graham G Giles
Factors in childhood as predictors of asthma in adult life BMJ 1994 Mark A Jenkins, John L Hopper, Glenn Bowes, John B Carlin, Louisa B Flander, Graham G Giles
Increase in the self-reported prevalence of asthma and hay fever in adults over the last generation: a matched parent-offspring study Australian Journal of Public Health 1995 John L Hopper, Mark A Jenkins, John B Carlin, Graham G Giles
Validation of Questionnaire and Bronchial Hyperresponsiveness against Respiratory Physician Assessment in the Diagnosis of Asthma International Journal of Epidemiology 1996 Mark A Jenkins, Jane R Clarke, John B Carlin, Colin F Robertson, John L Hopper, Marita F Dalton, Diane P Holst, Kevin Choi, Graham G Giles
Regressive logistic modeling of familial aggregation for asthma in 7,394 population-based nuclear families Genetic Epidemiology 1997 Mark A Jenkins, John L Hopper, Graham G Giles
Parity and decreased use of oral contraceptives as predictors of asthma in young women Clincal & Experimental Allergy 2006 Mark A. Jenkins, Shyamali C Dharmage, Louisa B Flander, Jo A. Douglass, A. M. Ugoni J. B. Carlin S. M. Sawyer, Graham G Giles, John L Hopper
Tracing 8,600 participants 36 years after recruitment at age seven for the Tasmanian Asthma Study Australian and New Zealand Journal of Medicine 2006 Cathryn Wharton, Shyamali C Dharmage, Mark A Jenkins, Gillian Dite, John L Hopper, Graham G Giles, Michael J Abramson, E Haydn Walters
Who remembers whether they had asthma as children? Journal of Asthma 2006 John A Burgess, E Haydn Walters, Graham B Byrnes, Cathryn Wharton, Mark A Jenkins, Michael J Abramson, John L Hopper, Shyamali C Dharmage
Childhood adiposity predicts adult-onset current asthma in females: a 25-yr prospective study The European Respiratory Journal 2007 John A Burgess, E Haydn Walters, Graham B Byrnes, Graham G Giles, Mark A Jenkins, Michael J Abramson, John L Hopper, Shyamali C Dharmage
Is childhood immunisation associated with atopic disease from age 7 to 32 years? Thorax 2007 Kazunori Nakajima, Shyamali C Dharmage, John B Carlin, Cathryn L Wharton, Mark A Jenkins, Graham G Giles, Michael J Abramson, Eugene Haydn Walters, John L Hopper
Breast-feeding and atopic disease: A cohort study from childhood to middle age The Journal of Allergy & Clinical Immunology 2007 Melanie C Matheson, Bircan Erbas, Aindralal Balasuriya, Mark A Jenkins, Cathryn L Wharton, Mimi Lai-Kuan Tang, Michael J Abramson, Eugene Haydn Walters, John L Hopper, Shyamali C Dharmage
Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study The Journal of Allergy & Clinical Immunology 2007 John A Burgess, Eugene Haydn Walters, Graham B Byrnes, Melanie C Matheson, Mark A Jenkins, Cathryn L Wharton, David P Johns, Michael J Abramson, John L Hopper, Shyamali C Dharmage
Childhood eczema and asthma incidence and persistence: a cohort study from childhood to middle age The Journal of Allergy & Clinical Immunology 2008 John A Burgess, Shyamali C Dharmage, Graham B Byrnes, Melanie C Matheson, Lyle C Gurrin, Cathryn L Wharton, David P Johns, Michael J Abramson, John L Hopper, E Haydn Walters
Relevance of the hygiene hypothesis to early vs. late onset allergic rhinitis Clincal & Experimental Allergy 2009 Melanie C Matheson, E Haydn Walters, Julie A Simpson, Cathryn L Wharton, A.âL. Ponsonby, David P Johns, Mark A Jenkins, Graham G Giles, John L Hopper, Michael J Abramson, Shyamali C Dharmage
Adherence to asthma management guidelines by middle-aged adults with current asthma Thorax 2009 R K Kandane-Rathnayake, Melanie C Matheson, Julie A Simpson, M L K Tang, David P Johns, Désirée Mészáros, Richard Wood-Baker, Ian Feather, Stephen Morrison, Mark A Jenkins, Graham G Giles, John L Hopper, Michael J Abramson, Shyamali C Dharmage, Eugene Haydn Walters
Childhood immunization and atopic disease into middle-age–a prospective cohort study Paediatric and Perinatal Epidemiology 2010 Melanie C Matheson, E Haydn Walters, John A Burgess, Mark A Jenkins, Graham G Giles, John L Hopper, Michael J Abramson, Shyamali C Dharmage
Poor lung function and tonsillectomy in childhood are associated with mortality from age 18 to 44 Respiratory Medicine 2010 Désirée Mészáros, Shyamali C Dharmage, Melanie C Matheson, A Venn, Cathryn L Wharton, David P Johns, Michael J Abramson, Graham G Giles, John L Hopper, Eugene Haydn Walters
Ambient wood smoke exposure and respiratory symptoms in Tasmania, Australia The Science of the total environment 2010 C M Bennett, Shyamali C Dharmage, Melanie Matheson, J L Gras, James Markos, Désirée Mészáros, John L Hopper, Eugene Haydn Walters, Michael J Abramson
Factors influencing asthma remission: a longitudinal study from childhood to middle age Thorax 2011 John A Burgess, Melanie C Matheson, Lyle C Gurrin, Graham B Byrnes, Kristie S Adams, Cathryn L Wharton, Graham G Giles, Mark A Jenkins, John L Hopper, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
Childhood eczema and rhinitis predict atopic but not nonatopic adult asthma: a prospective cohort study over 4 decades The Journal of Allergy & Clinical Immunology 2011 Pamela E Martin, Melanie C Matheson, Lyle Gurrin, John A Burgess, Nicholas Osborne, Adrian J Lowe, Stephen Morrison, Désirée Mészáros, Graham G Giles, Michael J Abramson, E Haydn Walters, Katrina J Allen, Shyamali C Dharmage
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma Lancet 2011 Manuel A R Ferreira, Melanie C Matheson, David L Duffy, Guy B Marks, Jennie Hui, Peter Le Souëf, Patrick Danoy, Svetlana Baltic, Dale R Nyholt, Mark Jenkins, Catherine Hayden, Gonneke Willemsen, Wei Ang, Mikko Kuokkanen, John Beilby, Faang Cheah, Eco J C de Geus, Adaikalavan Ramasamy, Sailaja Vedantam, Veikko Salomaa, Pamela A Madden, Andrew C Heath, John L Hopper, Peter M Visscher, Bill Musk, Stephen R Leeder, Marjo-Riitta Jarvelin, Craig Pennell, Dorret I Boomsma, Joel N Hirschhorn, Haydn Walters, Nicholas G Martin, Alan James, Graham Jones, Michael J Abramson, Colin F Robertson, Shyamali C Dharmage, Matthew A Brown, Grant W Montgomery, Philip J Thompson, Australian Asthma Genetics Consortium
Reasons for ongoing participation in a longitudinal cohort study Australian and New Zealand Journal of Public Health 2012 Christopher A. Barton, Cathryn L May, Desiree Mészáros, Melanie C. Matheson, Mark Jenkins, Graham Giles, John Hopper, E. Haydn Walters, Shyamali C. Dharmage, Michael J. Abramson
Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA Plos One 2012 Adaikalavan Ramasamy, Mikko Kuokkanen, Sailaja Vedantam, Zofia K. Gajdos, Alexessander Couto Alves, Helen N. Lyon, Manuel A. R. Ferreira, David P. Strachan, Jing Hua Zhao, Michael J. Abramson, Matthew A. Brown, Lachlan Coin, Shyamali C. Dharmage, David L. Duffy, Tari Haahtela, Andrew C. Heath, Christer Janson, Mika Kähönen, Kay-Tee Khaw, Jaana Laitinen, Peter Le Souef, Terho Lehtimäki, Australian Asthma Genetics Consortium collaborators, Pamela A. F. Madden, Guy B. Marks, Nicholas G. Martin, Melanie C. Matheson, Cameron D. Palmer, Aarno Palotie, Anneli Pouta, Colin F. Robertson, Jorma Viikari, Elisabeth Widen, Matthias Wjst, Deborah L. Jarvis, Grant W. Montgomery, Philip J. Thompson, Nick Wareham, Johan Eriksson, Pekka Jousilahti, Tarja Laitinen, Juha Pekkanen, Olli T. Raitakari, George T. O’Connor, Veikko Salomaa, Marjo-Riitta Jarvelin, Joel N. Hirschhorn.
Childhood infections and the risk of asthma over time: a longitudinal studyover 37 years Chest 2012 John A Burgess, Michael J Abramson, Lyle C Gurrin, Graham B Byrnes, Melanie C Matheson, Cathryn L May, Graham G Giles, David P Johns, John L Hopper, E Haydn Walters, Shyamali C Dharmage
Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data The Journal of Allergy & Clinical Immunology 2012 John L Hopper, Quang M Bui, Bircan Erbas, Melanie C Matheson, Lyle C Gurrin, John A Burgess, Adrian J Lowe, Mark A Jenkins, Michael J Abramson, E Haydn Walters, Graham G Giles, Shyamali C Dharmage
Genome-wide association study to identify genetic determinants of severe asthma Thorax 2012 Y I Wan, N R G Shrine, M Soler Artigas, L V Wain, J D Blakey, M F Moffatt, A Bush, K F Chung, W O C M Cookson, D P Strachan, L Heaney, B A H Al-Momani, A H Mansur, S Manney, N C Thomson, R Chaudhuri, C E Brightling, M Bafadhel, A Singapuri, R Niven, A Simpson, J W Holloway, P H Howarth, J Hui, A W Musk, A L James, the Australian Asthma Genetics Consortium, M A Brown, S Baltic, M A R Ferreira, P J Thompson, M D Tobin, I Sayers, I P Hall
The Interplay between the Effects of Lifetime Asthma, Smoking, and Atopy on Fixed Airflow Obstruction in Middle Age American Journal of Respiratory and Critical Care Medicine 2013 Jennifer L. Perret, Shyamali C. Dharmage, Melanie C. Matheson, David P. Johns, Lyle C. Gurrin, John A. Burgess, John Marrone, James Markos, Stephen Morrison, Iain Feather, Paul S. Thomas, Christine F. McDonald, Graham G. Giles, John L. Hopper, Richard Wood-Baker, Michael J. Abramson, Eugene H. Walters
Ambient wood smoke, traffic pollution and adult asthma prevalence and severity Respirology 2013 Dinh S Bui, John A Burgess, Melanie C Matheson, Bircan Erbas, Jennifer Perret, Stephen Morrison, Graham G Giles, John L Hopper, Paul S Thomas, James Markos, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
Occupational exposures and the development of new-onset asthma: a population-based cohort study from the ages of 13 to 44 years Journal of Occupation and Environmental Medicine 2013 Ryan F Hoy, John A Burgess, Geza Benke, Melanie Matheson, Stephen Morrison, Lyle Gurrin, E Haydn Walters, Shyamali C Dharmage, Michael J Abramson
Adult Serum Cytokine Concentrations and the Persistence of Asthma International Archives of Allergy and Immunology 2013 Kandane-Rathnayake R.K.,Tang M.L.K.,Simpson J.A., Burgess J.A., Mészáros D., Feather I, · Southey M.C, Schroen C.J, Hopper J, Morrison S.C, Giles G.G, Walters E.H, Dharmage S.C, Matheson M.C
Association between latitude and allergic diseases: a longitudinal study from childhood to middle-age Annals of Allergy, Asthma & Immunology 2013 Vicka Oktaria, Shyamali C Dharmage, John A Burgess, Julie A Simpson, Stephen Morrison, Graham G Giles, Michael J Abramson, E Haydn Walters, Melanie C Matheson
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype The Journal of Allergy & Clinical Immunology 2014 Ferreira MA, Matheson MC, Tang CS, Granell R, Ang W, Hui J, Kiefer AK, Duffy DL, Baltic S, Danoy P, Bui M, Price L, Sly PD, Eriksson N, Madden PA, Abramson MJ, Holt PG, Heath AC, Hunter M, Musk B, Robertson CF, Le Souef P, Montgomery GW, Henderson AJ, Tung JY, Dharmage SC, Brown MA, James A, Thompson PJ, Pennell C, Martin NG, Evans DM, Hinds DA, Hopper JL.
Domestic airborne pollutants and asthma and respiratory symptoms in middle age Respirology 2014 Désirée Mészáros, Burgess J, Walters EH, Johns D, Markos J, Giles G, Hopper J, Abramson M, Dharmage S, Matheson M
The independent and combined effects of lifetime smoke exposures and asthma as they relate to COPD Expert Review of Respiratory Medicine 2014 Perret JL, Walters EH, Abramson MJ, McDonald CF, Dharmage SC
Hormonal contraception increases risk of asthma among obese but decreases it among nonobese subjects: a prospective, population-based cohort study ERJ Open Research 2015 Melanie C. Matheson, John A. Burgess, Melisa Y.Z. Lau, Adrian J. Lowe, Lyle C. Gurrin, John L. Hopper, Graham G. Giles, David P. Johns, E. Haydn Walters, Michael J. Abramson, Francisco Gómez Real, Shyamali C. Dharmage
Current asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study International Journal of Chronic Obstructive Pulmonary Disease 2016 Dharmage SC, Perret JL, Burgess JA, Lodge CJ, Johns DP, Thomas PS, Giles GG, Hopper JL, Abramson MJ, Walters EH, Matheson MC
Childhood body mass index and adult mammographic density measures that predict breast cancer risk Breast Cancer Research and Treatment 2016 Hopper JL, Nguyen TL, Stone J, Aujard K, Matheson MC, Abramson MJ, Burgess JA, Walters EH, Dite GS, Bui M, Evans C, Makalic E, Schmidt DF, Ward G, Jenkins MA, Giles GG, Dharmage SC, Apicella C
Cohort Profile: The Tasmanian Longitudinal Health STUDY (TAHS) International Journal of Epidemiology 2016 Matheson MC, Abramson MJ, Allen K, Benke G, Burgess JA, Dowty JG, Erbas B, Feather IH, Frith PA, Giles GG, Gurrin LC, Hamilton GS, Hopper JL, James AL, Jenkins MA, Johns DP, Lodge CJ, Lowe AJ, Markos J, Morrison SC, Perret JL, Southey MC, Thomas PS, Thompson BR, Wood-Baker R, Haydn Walters E, Dharmage SC
Preterm birth and low birth weight continue to increase the risk of asthma from age 7 to 43 Journal of Asthma 2016 Matheson MC, AL DO, Burgess JA, Giles GG, Hopper JL, Johns DP, Abramson MJ, Walters EH, Dharmage SC
Mould-sensitized adults have lower Th2 cytokines and a higher prevalence of asthma than those sensitized to other aeroallergens Allergy 2016 Matheson MC, Reece JC, Kandane-Rathnayake RK, Tang ML, Simpson JA, Feather IH, Southey MC, Tsimiklis H, Hopper JL, Morrison SC, Giles GG, Walters EH, Dharmage SC
Mother’s smoking and complex lung function of offspring in middle age: A cohort study from childhood Respirology 2016 Perret JL, Walters H, Johns D, Gurrin L, Burgess J, Lowe A, Thompson B, Markos J, Morrison S, Thomas P, McDonald C, Wood-Baker R, Hopper J, Svanes C, Giles G, Abramson M, Matheson M, Dharmage S
Clinical and functional differences between early-onset and late-onset adult asthma: a population-based Tasmanian Longitudinal Health Study Thorax 2016 Tan DJ, Walters EH, Perret JL, Burgess JA, Johns DP, Lowe AJ, Lodge CJ, Hayati Rezvan P, Simpson JA, Morrison S, Thompson BR, Thomas PS, Feather I, Giles GG, Hopper JL, Abramson MJ, Matheson MC, Dharmage SC
Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age The Journal of Allergy & Clinical Immunology 2017 Bowatte G, Lodge CJ, Knibbs LD, Lowe AJ, Erbas B, Dennekamp M, Marks GB, Giles G, Morrison S, Thompson B, Thomas PS, Hui J, Perret JL, Abramson MJ, Walters H, Matheson MC, Dharmage SC
The interaction between farming/rural environment and TLR2, TLR4, TLR6 and CD14 genetic polymorphisms in relation to early- and late-onset asthma Scientific Report 2017 Melisa Y. Z. Lau, Shyamali C. Dharmage, John A. Burgess, Aung K. Win, Adrian J. Lowe, Caroline Lodge, Jennifer Perret, Jennie Hui, Paul S. Thomas, Stephen Morrison, Graham G. Giles, John Hopper, Michael J. Abramson, E. Haydn Walters, Melanie C. Matheson
Long-term traffic-related air pollution exposure is associated with increased risk of asthma and poor lung function in middle age European Journal of Respiratory 2017 Bowatte G, Erbas B, Lodge CJ, Knibbs LD, Gurrin LC, Marks GB, Thomas P, Johns DP, Giles GG, Hui J, Dennekamp M, Perret J, Abramson MJ, Walters EH, Matheson MC, Dharmage SC
The Dose-Response Association between Nitrogen Dioxide Exposure and Serum Interleukin-6 Concentrations International Journal of Molecular Science 2017 Jennifer L Perret, Gayan Bowatte, Caroline J Lodge, Luke D Knibbs, Lyle C Gurrin, Rangi Kandane-Rathnayake, David P Johns, Adrian J Lowe, John A Burgess, Bruce R Thompson, Paul S Thomas, Richard Wood-Baker, Stephen Morrison, Graham G Giles, Guy Marks, James Markos, Mimi L K Tang, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Shyamali C Dharmage
Bronchial hyperresponsiveness and obesity in middle age: insights from an Australian cohort The European Respiratory Journal 2017 John A Burgess, Melanie C Matheson, Fei Diao, David P Johns, Bircan Erbas, Adrian J Lowe, Lyle C Gurrin, Caroline J Lodge, Paul S Thomas, Stephen Morrison, Bruce R Thompson, Iain Feather, Jennifer L Perret, Michael J Abramson, Graham G Giles, John L Hopper, Shyamali C Dharmage, Eugene H Walters
Occupational exposures to solvents and metals are associated with fixed airflow obstruction Scandinavian Journal of work, environment & health 2017 Sheikh M Alif, Shyamali C Dharmage, Geza Benke, Martine Dennekamp, John A Burgess, Jennifer L Perret, Caroline J Lodge, Stephen Morrison, David P Johns, Graham G Giles, Lyle C Gurrin, Paul S Thomas, John L Hopper, Richard Wood-Baker, Bruce R Thompson, Iain H Feather, Roel Vermeulen, Hans Kromhout, E Haydn Walters, Michael J Abramson, Melanie C Matheson
Occupational exposure to pesticides are associated with fixed airflow obstruction in middle-age Thorax 2017 Sheikh M Alif, Shyamali C Dharmage, Geza Benke, Martine Dennekamp, John A Burgess, Jennifer L Perret, Caroline J Lodge, Stephen Morrison, David Peter Johns, Graham G Giles, Lyle C Gurrin, Paul S Thomas, John Llewelyn Hopper, Richard Wood-Baker, Bruce R Thompson, Iain H Feather, Roel Vermeulen, Hans Kromhout, E Haydn Walters, Michael J Abramson, Melanie Claire Matheson
Childhood Lung Function Predicts Adult Chronic Obstructive Pulmonary Disease and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome American Journal of Respiratory and Critical Care Medicine 2017 Dinh S Bui, John A Burgess, Adrian J Lowe, Jennifer L Perret, Caroline J Lodge, Minh Bui, Stephen Morrison, Bruce R Thompson, Paul S Thomas, Graham G Giles, Judith Garcia-Aymerich, Debbie Jarvis, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Shyamali C Dharmage
Traffic-related air pollution exposure over a 5-year period is associated with increased risk of asthma and poor lung function in middle age European Journal of Respiratory 2017 Gayan Bowatte, Bircan Erbas, Caroline J Lodge, Luke D Knibbs, Lyle C Gurrin, Guy B Marks, Paul S Thomas, David P Johns, Graham G Giles, Jennie Hui, Martine Dennekamp, Jennifer L Perret, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Shyamali C Dharmage
Preterm birth and low birth weight continue to increase the risk of asthma from age 7 to 43 Journal of Asthma 2017 Melanie C Matheson, Ana López-PolÃn D Olhaberriague, John A Burgess, Graham G Giles, John L Hopper, David P Johns, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
Traffic related air pollution and development and persistence of asthma and low lung function Environment International 2018 Gayan Bowatte, Caroline J Lodge, Luke D Knibbs, Bircan Erbas, Jennifer L Perret, Bin Jalaludin, Geoffrey G Morgan, Dinh S Bui, Graham G Giles, Garun S Hamilton, Richard Wood-Baker, Paul Thomas, Bruce R Thompson, Melanie C Matheson, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
NO x in exhaled breath condensate is related to allergic sensitization in young and middle-aged adults Clinical & Experimental Epidemiology 2018 Fahad M Aldakheel, Jane E Bourke, Paul S Thomas, Melanie C Matheson, Michael J Abramson, Garun S Hamilton, Caroline J Lodge, Bruce R Thompson, E Haydn Walters, Katrina J Allen, Bircan Erbas, Jennifer L Perret, Shyamali C Dharmage, Adrian J Lowe
Childhood measles contributes to post-bronchodilator airflow obstruction in middle-aged adults: A cohort study Respirology 2018 Jennifer L Perret, Melanie C Matheson, Lyle C Gurrin, David P Johns, John A Burgess, Bruce R Thompson, Adrian J Lowe, James Markos, Stephen S Morrison, Christine F McDonald, Richard Wood-Baker, Cecilie Svanes, Paul S Thomas, John L Hopper, Graham G Giles, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life Lancet Respiratory Medicine 2018 Dinh S Bui, Caroline J Lodge, John A Burgess, Adrian J Lowe, Jennifer Perret, Minh Q Bui, Gayan Bowatte, Lyle Gurrin, David P Johns, Bruce R Thompson, Garun S Hamilton, Peter A Frith, Alan L James, Paul S Thomas, Deborah Jarvis, Cecilie Svanes, Melissa Russell, Stephen C Morrison, Iain Feather, Katrina J Allen, Richard Wood-Baker, John Hopper, Graham G Giles, Michael J Abramson, Eugene H Walters, Melanie C Matheson, Shyamali C Dharmage
Childhood Respiratory Risk Factor Profiles and Middle-Age Lung Function: A Prospective Cohort Study from the First to Sixth Decade Annals of the American Thoracic Society 2018 Dinh S Bui, Haydn E Walters, John A Burgess, Jennifer L Perret, Minh Q Bui, Gayan Bowatte, Adrian J Lowe, Melissa A Russell, Bruce R Thompson, Garun S Hamilton, Alan L James, Graham G Giles, Paul S Thomas, Debbie Jarvis, Cecilie Svanes, Judith Garcia-Aymerich, Bircan Erbas, Peter A Frith, Katrina J Allen, Michael J Abramson, Caroline J Lodge, Shyamali C Dharmage
Residential Exposure to Outdoor Air Pollution and Post-bronchodilator Lung Function Deficits in Mid-Adult Life American Journal of Respiratory and Critical Care Medicine 2019 Jennifer L Perret, Gayan Bowatte, Luke D Knibbs, David P Johns, Caroline J Lodge, Adrian J Lowe, Dinh S Bui, Melanie C Matheson, Bruce R Thompson, Graham G Giles, E Haydn Walters, Michael J Abramson, Shyamali C Dharmage
Occupational exposure to solvents and lung function decline: A population based study Thorax 2019 Sheikh M Alif, Shyamali Dharmage, Geza Benke, Martine Dennekamp, John Burgess, Jennifer L Perret, Caroline Lodge, Stephen Morrison, David Peter Johns, Graham Giles, Lyle Gurrin, Paul S Thomas, John Llewelyn Hopper, Richard Wood-Baker, Bruce Thompson, Iain Feather, Roel Vermeulen, Hans Kromhout, Debbie Jarvis, Judith Garcia Aymerich, E Haydn Walters, Michael J Abramson, Melanie Claire Matheson
Detecting sleep apnoea syndrome in primary care with screening questionnaires and the Epworth sleepiness scale The Medical Journal of Australia 2019 Chamara V Senaratna, Jennifer L Perret, Adrian Lowe, Gayan Bowatte, Michael J Abramson, Bruce Thompson, Caroline Lodge, Melissa Russell, Garun S Hamilton, Shyamali C Dharmage
Nocturnal symptoms perceived as asthma are associated with obstructive sleep apnoea risk, but not bronchial hyper-reactivity Respirology 2019 Chamara V Senaratna, E Haydn Walters, Garun Hamilton, Adrian J Lowe, Caroline Lodge, John Burgess, Bircan Erbas, Graham G Giles, Paul Thomas, Michael J Abramson, Bruce Thompson, Jennifer L Perret, Shyamali C Dharmage
Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization Clinical & Experimental Epidemiology 2019 Melisa Y Z Lau, Shyamali C Dharmage, John A Burgess, Aung K Win, Adrian J Lowe, Caroline J Lodge, Jennifer Perret, Jennie Hui, Paul S Thomas, Graham Giles, Bruce R Thompson, Michael J Abramson, E Haydn Walters, Melanie C Matheson
Comparison of apnoea-hypopnoea index and oxygen desaturation index when identifying obstructive sleep apnoea using type-4 sleep studies Journal of Sleep Research 2019 Chamara V Senaratna, Adrian Lowe, Jennifer L Perret, Caroline Lodge, Gayan Bowatte, Michael J Abramson, Bruce R Thompson, Garun Hamilton, Shyamali C Dharmage
Trajectories of asthma and allergies from 7 years to 53 years and associations with lung function and extrapulmonary comorbidity profiles: a prospective cohort study Lancet Respiratory Medicine 2020 Dinh S Bui, Caroline J Lodge, Jennifer L Perret, Adrian Lowe, Garun S Hamilton, Bruce Thompson, Graham Giles, Daniel Tan, Bircan Erbas, Jane Pirkis, Flavia Cicuttini, Raisa Cassim, Gayan Bowatte, Paul Thomas, Judith Garcia-Aymerich, John Hopper, Michael J Abramson, Eugene H Walters, Shyamali C Dharmage
Lifetime Risk Factors for Pre- and Post-Bronchodilator Lung Function Decline. A Population-based Study Annals of the American Thoracic Society 2020 Dinh S Bui, Jennifer L Perret, E Haydn Walters, Michael J Abramson, John A Burgess, Minh Q Bui, Gayan Bowatte, Adrian J Lowe, Melissa A Russell, Sheikh M Alif, Bruce R Thompson, Garun S Hamilton, Graham G Giles, Paul S Thomas, Stephen Morrison, David P Johns, Luke D Knibbs, Jan-Paul Zock, Alessandro Marcon, Judith Garcia-Aymerich, Bircan Erbas, Deborah Jarvis, Cecilie Svanes, Caroline J Lodge, Shyamali C Dharmage
Childhood pneumonia, pleurisy and lung function: a cohort study from the first to sixth decade of life Thorax 2020 Jennifer L Perret, Caroline J Lodge, Adrian J Lowe, David P Johns, Bruce R Thompson, Dinh S Bui, Lyle C Gurrin, Melanie C Matheson, Christine F McDonald, Richard Wood-Baker, Cecilie Svanes, Paul S Thomas, Graham G Giles, Anne B Chang, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
Early Age at Natural Menopause Is Related to Lower Post-Bronchodilator Lung Function. A Longitudinal Population-based Study Annals of the American Thoracic Society 2020 Brittany Campbell, Dinh S Bui, Julie A Simpson, Caroline J Lodge, Adrian J Lowe, Gayan Bowatte, Bénédicte Leynaert, Francisco Gómez Real, Paul S Thomas, Graham G Giles, David P Johns, Judith Garcia-Aymerich, John L Hopper, Debbie Jarvis, Michael J Abramson, E Haydn Walters, Jennifer L Perret, Shyamali C Dharmage
Early menarche is associated with lower adult lung function: A longitudinal cohort study from the first to sixth decade of life Respirology 2020 Brittany Campbell, Julie A Simpson, Dinh S Bui, Caroline J Lodge, Adrian J Lowe, Melanie C Matheson, Gayan Bowatte, John A Burgess, Garun S Hamilton, Benedicte Leynaert, Francisco Gómez Real, Paul S Thomas, Graham G Giles, Peter A Frith, David P Johns, Gita Mishra, Judith Garcia-Aymerich, Debbie Jarvis, Michael J Abramson, E Haydn Walters, Jennifer L Perret, Shyamali C Dharmage
Non-pharmacological management of adult asthma in Australia: cross-sectional analysis of a population-based cohort study The Journal of Asthma 2020 Daniel J Tan, John A Burgess, Jennifer L Perret, Dinh S Bui, Michael J Abramson, Shyamali C Dharmage, E Haydn Walters
Exposure to household air pollution over 10 years is related to asthma and lung function decline European Journal of Respiratory 2021 Xin Dai, Dinh S Bui, Jennifer L Perret, Adrian J Lowe, Peter A Frith, Gayan Bowatte, Paul S Thomas, Graham G Giles, Garun S Hamilton, Helen Tsimiklis, Jennie Hui, John Burgess, Aung K Win, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage, Caroline J Lodge
Association between ambient air pollution and development and persistence of atopic and non-atopic eczema in a cohort of adults Allergy 2021 Diego J Lopez, Caroline J Lodge, Dinh S Bui, Nilakshi T Waidyatillake, John C Su, Jenny L Perret, Luke D Knibbs, Bircan Erbas, Paul S Thomas, Garun S Hamilton, Bruce R Thompson, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage, Gayan Bowatte, Adrian J Lowe
Bronchodilator reversibility as a diagnostic test for adult asthma: findings from the population-based Tasmanian Longitudinal Health Study ERJ Open Research 2021 Daniel J Tan, Caroline J Lodge, Adrian J Lowe, Dinh S Bui, Gayan Bowatte, David P Johns, Garun S Hamilton, Paul S Thomas, Michael J Abramson, E Haydn Walters, Jennifer L Perret, Shyamali C Dharmage
Protein levels, air pollution and vitamin D deficiency: links with allergy ERJ Open Research 2021 Yong Song, E. Haydn Walters, Michael J. Abramson, Gayan Bowatte, Dinh S. Bui, Jennifer Perret, Iain Feather, Luke D. Knibbs, Richard Wilson, David S. Nichols, Shyamali C. Dharmage, Graeme R. Zosky
Childhood lung function as a determinant of menopause-dependent lung function decline Maturitas 2021 Kai Triebner, Dinh Bui, Eugene Haydn Walters, Michael J Abramson, Gayan Bowatte, Brittany Campbell, Payam Dadvand, Bircan Erbas, David P Johns , Bénédicte Leynaert, Caroline J Lodge, Adrian J Lowe, Jennifer L Perret, Steinar Hustad, Francisco Gómez Real, Shyamali C Dharmage
Lung function trajectory and biomarkers in the Tasmanian Longitudinal Health Study ERJ Open Research 2021 Dinh S Bui, Alvar Agusti, Haydn Walters, Caroline Lodge, Jennifer L Perret, Adrian Lowe, Gayan Bowatte, Raisa Cassim, Garun S Hamilton, Peter Frith, Alan James, Paul S Thomas, Debbie Jarvis, Michael J Abramson, Rosa Faner, Shyamali C Dharmage
Ten-year prediction model for post-bronchodilator airflow obstruction and early detection of COPD: development and validation in two middle-aged population-based cohorts BMJ 2021 Jennifer L Perret, Don Vicendese, Koen Simons, Debbie L Jarvis, Adrian J Lowe, Caroline J Lodge, Dinh S Bui, Daniel Tan, John A Burgess, Bircan Erbas, Adrian Bickerstaffe, Kerry Hancock, Bruce R Thompson, Garun S Hamilton, Robert Adams, Geza P Benke, Paul S Thomas, Peter Frith, Christine F McDonald, Tony Blakely, Michael J Abramson, E Haydn Walters, Cosetta Minelli, Shyamali C Dharmage, TAHS and ECRHS Investigator Groups
Parental preconception BMI trajectories from childhood to adolescence and asthma in the future offspring The Journal of Allergy & Clinical Immunology 2022 Gayan Bowatte, Dinh S Bui, Sajith Priyankara, Adrian J Lowe, Jennifer L Perret, Caroline J Lodge, Garun S Hamilton, Bircan Erbas, Paul Thomas, Bruce Thompson, Vivi Schlünssen, David Martino, John W Holloway, Cecilie Svanes, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
Impact of lifetime body mass index trajectories on the incidence and persistence of adult asthma The European respiratory journal 2022 Gulshan Bano Ali, Adrian J Lowe, Jennifer L Perret, E Haydn Walters, Caroline J Lodge, David Johns, Alan James, Bircan Erbas, Garun S Hamilton, Gayan Bowatte, Richard Wood-Baker, Michael J Abramson, Dinh S Bui, Shyamali C Dharmage
Association between very to moderate preterm births, lung function deficits, and COPD at age 53 years: analysis of a prospective cohort study Lancet Respiratory Medicine 2022 Dinh S Bui, Jennifer L Perret, E Haydn Walters, Caroline J Lodge, Gayan Bowatte, Garun S Hamilton, Bruce R Thompson, Peter Frith, Bircan Erbas, Paul S Thomas, David P Johns, Richard Wood-Baker, John L Hopper, Peter G Davis, Michael J Abramson, Adrian J Lowe, Shyamali C Dharmage
Pre-pubertal smoke exposure of fathers and increased risk of offspring asthma: a possible transgenerational effect European Respiratory Journal 2022 Jiacheng Liu, Gayan Bowatte, Jonathan Pham, Jennifer L. Perret, John W. Holloway, Adrian J. Lowe, John A. Burgess, Cecilie Svanes, Paul Thomas, Melissa A. Russell, Bircan Erbas, Caroline J. Lodge, David Martino, Gita D. Mishra, Michael J. Abramson, Eugene H. Walters, Shyamali C. Dharmage, Dinh S. Bui
